General body
General body is the apex body of the Council which was being reconstituted in August 2006. It consist of 61 members comprising ministers and secretaries of different state department and head of the departments of water resources, PHE, PWD, Forest, Agriculture, Industry and Technical Education. In addition four vice-chancellors from universities, eminent scientist in science, sociology and medical sciences are nominated as member by the president. Representatives from national level research organization are also nominated.
The General Body :-
| 1. | Chief Minister, Madhya Pradesh. | President |
| 2. | Vice - President (to be nominated by the President) | Vice - President |
| 3. | Minister / State Minister / Deputy Minister for Science and Technology, Madhya Pradesh as may be nominated by the President. | Member |
| 4. | Minister / State Minister / Deputy Minister for Education, Madhya Pradesh as may be nominated by the President. | Member |
| 5. | Minister / State Minister / Deputy Minister for Finance, Madhya Pradesh as may be nominated by the President. | Member |
| 6. | Minister / State Minister / Deputy Minister for Industry, Madhya Pradesh as may be nominated by the President. | Member |
| 7. | Minister / State Minister / Deputy Minister for Agriculture, Madhya Pradesh as may be nominated by the President. | Member |
| 8. | Minister / State Minister / Deputy Minister for Planning, Madhya Pradesh as may be nominated by the President. | Member |
| 9. | Chief Secretary, Government of Madhya Pradesh. | Member |
| 10. | Secretary to Government of Madhya Pradesh, Science and Technology Department. | Member |
| 11. | Secretary to Government of Madhya Pradesh, Education Department | Member |
| 12. | Secretary to Government of Madhya Pradesh, Finance Department. | Member |
| 13. | Secretary to Government of Madhya Pradesh, Planning, Economics and Statistics Department. | Member |
| 14. | Secretary to Government of Madhya Pradesh, Agriculture Department. | Member |
| 15. | Secretary to Government of Madhya Pradesh, Commerce and Industry Department. | Member |
| 16. | Secretary to Government of Madhya Pradesh, Rural Development Department. | Member |
| 17. | Secretary to Government of Madhya Pradesh, Housing & Environment Department. | Member |
| 18. | Chairman, Madhya Pradesh Electricity Board. | Member |
| 19. | Secretary to Government of Madhya Pradesh, Manpower Planning Department. | Member |
| 20. | Vice Chancellors from the Universities of Madhya Pradesh | Member |
| 21. | Vice Chancellor , Jawaharlal Nehru Krishi Vishwa Vidhyalaya, Jabalpur. | Member |
| 22. | Director, Maulana Azad College of Technology, Bhopal. | Member |
| 23. | Four eminent scientist, to be nominated by the president. | Member |
| 24. | Two eminent social Scientist , to be nominated by the President. | Member |
| 25. | Two eminent persons from the medical profession to be nominated by the President. | Member |
| 26. | Engineer-in-chief, Irrigation, Madhya Pradesh | Member |
| 27. | Engineer-in-chief, Public Health Engineering, Madhya Pradesh. | Member |
| 28. | Engineer-in-chief, Public Work Department, Madhya Pradesh. | Member |
| 29. | Principal Chief Conservator of Forest , Madhya Pradesh. | Member |
| 30. | Director of Agriculture, Madhya Pradesh. | Member |
| 31. | Director of Industries, Madhya Pradesh. | Member |
| 32. | Director of Technical Education, Madhya Pradesh. | Member |
| 33. | Three progressive agriculturist to be nominated by President- | Member |
| 34. | Three distinguish industrialist or Manufactures to be nominated by the President | Member |
| 35. | Two representatives of Public Sector undertakings of the State Government, to be nominated by the President. | Member |
| 36. | Director of Kishore Bharti, Hosangabad. | Member |
| 37. | Two representatives of Public Sector undertakings of the Government of India engaged in R&D activities, to be nominated by the President. | Member |
| 38. | A representative of the Department of Science & Technology, Government of India. | Member |
| 39. | A representative of C.S.I.R. Government of India. | Member |
| 40. | A representative of Indian National Science Academy. | Member |
| 41. | A representative of the Indian Council of Social Science Research. | Member |
| 42. | A representative of the Indian Council of Agriculture Research. | Member |
| 43. | A representative of the Indian Council of Medical Research. | Member |
| 44. | Director General of Madhya Pradesh, Council of Science & Technology. | Member-Secretary |
| 45. | Eminent scientists from different fields | Member |